Hybridization-based capture of pathogen mRNA enables paired host-pathogen transcriptional analysis

Proteome analysis of host-pathogen interactions: Investigation of pathogen responses to the host cell environment.

Infectious diseases are still a major health risk, and thus a better understanding of the interaction between human host cells and pathogenic microbes is urgently required. Since the interplay between both partners is highly complex, genome-wide analysis by OMICs approaches will likely make a major contribution to the elucidation of the pathophysiology of infection processes. In the concert of ...

Mining Host-Pathogen Interactions

containing HPI information and another abstract that does not. Using a training set of pre-annotated abstracts, the system can then learn how to efficiently discriminate between these two abstract types. Moreover, the same characteristic features can be calculated for the individual sentences in the abstract. Thus, we can use the same supervised-learning approach to solve Tasks 1 and 2. Finally...

Host-pathogen systems biology.

Unlike traditional biological research that focuses on a small set of components, systems biology studies the complex interactions between a large number of genes, proteins and other elements of biological networks and systems. Host-pathogen systems biology examines the interactions between the components of two distinct organisms, either a microbial or viral pathogen and its animal host or two...

Pathogen Reduction of Plasma

Host-Pathogen Interactions of Retroviruses

1Virus-Cell Interaction Section, HIV Drug Resistance Program, National Cancer Institute at Frederick, Frederick, MD 21702, USA 2Microbiology and Physiological Systems, University of Massachusetts Medical School, Worcester, MA 01655, USA 3Department of Microbiology, Boston University School of Medicine, Boston, MA 02118, USA 4Center for Virology, Burnet Institute, Melbourne, VIC 3004, Australia ...